Year: 2026 | Month: January-March | Volume: 11 | Issue: 1 | Pages: 45-52
DOI: https://doi.org/10.52403/gijhsr.20260107
Comparative Efficacy of Chhinnadi Kwath and Devdarvyadi Ghrit Nasya in the Management of Ardhavabhedaka (Migraine): A Randomized Clinical Trial
Dr. Annupriya Jakhar1, Prof. (Dr.) Pramod Kumar Mishra2, Dr. Ayushi Bhaskar3
1MD Scholar, PG Department of Kayachikitsa, PGIA, DSRRAU, Jodhpur
2Professor and HOD, PG Department of Kayachikitsa, PGIA, DSRRAU, Jodhpur
3Assistant Professor, PG Department of Kayachikitsa, PGIA, DSRRAU, Jodhpur
Corresponding Author: Dr. Annupriya Jakhar
ABSTRACT
Background: Ardhavabhedaka, a medical condition which is mentioned in ancient Ayurvedic texts, which is similar to migraine, is a common neurological ailment that leads to considerable disability. Ayurveda provides a variety of treatment options, such as oral decoctions (Kwath) and nasal therapies (Nasya).
Objective: To evaluate the therapeutic effects of oral Chhinnadi Kwath and Devdarvyadi Ghrit Nasya in the treatment of Ardhavabhedaka.
Methods: A clinical trial with a randomized, open-label, parallel-group design was carried out involving 30 diagnosed participants, who were evenly divided into two groups. Group A was administered Chhinnadi Kwath (48 ml orally twice a day), while Group B received Devdarvyadi Ghrit Nasya (6 drops in each nostril every morning). The treatment lasted for 60 days. The primary outcomes assessed were changes in the severity, duration, and frequency of attacks, evaluated on a scale from 0 to 4. Statistical analysis was conducted using suitable non-parametric tests, such as the Chi-square and Fisher’s exact test, along with paired t-tests.
Results: Both groups experienced statistically significant enhancements in all pain metrics from the initial assessment (p<0.005). When comparing the groups, it was found that Chhinnadi Kwath led to a notably greater reduction in pain severity than Devdarvyadi Ghrit Nasya (p=0.035). The improvements in the duration of pain and the frequency of attacks were similar between the groups (p>0.05). The baseline demographic characteristics were mostly similar, although there were significant differences in Ayurvedic parameters such as Koshtha (bowel type, p=0.027) and Prakriti (body constitution, p=0.004).
Conclusion: Both Chhinnadi Kwath and Devdarvyadi Ghrit Nasya are effective interventions for Ardhavabhedaka. Chhinnadi Kwath demonstrated superior efficacy in reducing the intensity of pain. The findings validate the clinical utility of these classical formulations and underscore the importance of personalized Ayurvedic assessment in treatment planning.
Keywords: Ardhavabhedaka; Migraine; Chhinnadi Kwath; Devdarvyadi Ghrit Nasya; Ayurveda; Randomized Clinical Trial; Pain Management.